...the scientific attitude implies what I call the postulate of objectivity—that is to say, the fundamental postulate that there is no plan, that there is no intention in the universe. Now, this is basically incompatible with virtually all the religious or metaphysical systems whatever, all of which try to show that there is some sort of harmony between man and the universe and that man is a product—predictable if not indispensable—of the evolution of the universe.
There are 100 billion neurons in the adult human brain, and each neuron makes something like 1,000 to 10,000 contacts with other neurons in the brain. Based on this, people have calculated that the number of permutations and combinations of brain activity exceeds the number of elementary particles in the universe.
Real misanthropes are not found in solitude, but in the world; since it is experience of life, and not philosophy, which produces real hatred of mankind.
If I were to give a prize for the single best idea anybody ever had, I'd give it to Darwin for the idea of natural selection - ahead of Newton, ahead of Einstein - because his idea unites the two most disparate features of our universe: the world of purposeless, meaningless matter and motion, particles jostling on the one side, and the world of meaning and purpose, design on the other.
Depression’s defining symptom is anhedonia, the inability to feel, anticipate, or pursue pleasure. Chronic stress depletes the mesolimbic system of dopamine, generating anhedonia. The link between childhood adversity and adult depression involves both organizational effects on the developing mesolimbic system and elevated adult glucocorticoid levels, which can deplete dopamine.
But if one observes, one will see that the body has its own intelligence; it requires a great deal of intelligence to observe the intelligence of the body.